Third, recent studies have demonstrated that the genetic deficiency of HO-2 does not accentuate the vasoconstrictive effects of ANG II on renal blood flow (38)

Third, recent studies have demonstrated that the genetic deficiency of HO-2 does not accentuate the vasoconstrictive effects of ANG II on renal blood flow (38). a stressed organ (by ANG II), but not that of the unstressed organ, requires intact renal HO activity, even when the imposed stress neither induces HO-1 nor HO activity. These …