However, PARP1 has also been reported to prevent excessive control of DNA at stalled replication forks by MRE11 (REF

However, PARP1 has also been reported to prevent excessive control of DNA at stalled replication forks by MRE11 (REF. mediating numerous aspects of DNA rate of metabolism, such as single-strand break restoration, nucleotide excision restoration, double-strand break restoration and the stabilization of replication forks, and in modulating chromatin structure. Cells are revealed constantly to numerous …